Can I take peptides?

These four conditions rule out peptides entirely. They are not negotiable, not class-specific, and not waivable with a lower dose. If any of these apply, peptides are off the table.

• Active cancer or history of cancer
• Currently pregnant or breastfeeding
• Under 18 years old
• Severe kidney or liver disease

The GLP-1 class — including retatrutide, tirzepatide, and semaglutide — has its own exclusion set on top of the general list. The thyroid and pancreatic items are the most commonly missed.

• Personal or family history of medullary thyroid carcinoma (MTC)
• Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
• History of pancreatitis
• Type 1 diabetes
• Severe gastrointestinal disease

BPC-157 and TB-500 are generally well tolerated. The two cautions below are relative, not absolute — they warrant a clinician conversation rather than a hard exclusion.

• Active cancer (theoretical growth concern — BPC-157 promotes angiogenesis)
• On blood thinners (may affect clotting pathways)

Any of the following should prompt a physician consult before starting any peptide. None of them are an automatic no — they are reasons to get a second opinion before injecting.

1. C01You have any chronic medical condition
2. C02You take prescription medications (check for interactions)
3. C03You have a history of eating disorders
4. C04You have cardiovascular disease
5. C05You have or had any endocrine disorders
6. C06You are unsure about any contraindication listed above

A reasonable candidate clears all six items below. This is a screening checklist, not a substitute for a clinician — but it is the minimum self-audit before reading the protocol guide.

• No active cancer
• No thyroid cancer history (for GLP-1s)
• Not pregnant or breastfeeding
• No severe organ disease (kidney, liver)
• Over 18 years old
• No history of pancreatitis (for GLP-1s)