CJC-1295 with DAC (Drug Affinity Complex) is a modified form of Growth Hormone Releasing Hormone (GHRH) that includes a Drug Affinity Complex, a chemical modification that allows it to bind to albumin in the blood, dramatically extending its half-life from minutes to 6–8 days. Browse the full peptide library for related GH compounds.
This long half-life enables once or twice weekly dosing, creating what is known as a "GH bleed," a sustained elevation in growth hormone levels rather than sharp pulsatile spikes. This is fundamentally different from CJC-1295 without DAC, which produces short, natural-pattern GH pulses.
The sustained GH elevation from CJC-1295 with DAC is preferred by users seeking body composition changes (more muscle, less fat) over the long-term, as it maintains growth factor levels more consistently. For clean, pulsatile GH release, consider stacking with ipamorelin. For clinically validated visceral fat reduction, tesamorelin has FDA approval for that specific indication. However, some argue that constant GH elevation is less physiological than pulsatile release.