CJC-1295 (No DAC)
Category
Growth Hormone
Frequency
1–3x daily
Research
Research Grade
What is CJC-1295 (No DAC)
CJC-1295 without DAC (also known as Modified GRF 1-29 or Mod GRF 1-29) is a truncated, stabilized form of GHRH (Growth Hormone Releasing Hormone) with a half-life of approximately 30 minutes. Unlike CJC-1295 with DAC, it does not bind to albumin and is cleared relatively quickly from the body. Browse the full peptide library for related GH compounds.
This shorter half-life means it produces a sharp, pulsatile GH release that more closely mimics the natural pattern of GH secretion — a burst every few hours. When combined with Ipamorelin (which activates the GH secretagogue receptor), the two peptides work synergistically to produce significantly higher and more sustained GH pulses than either can achieve alone.
CJC-1295 (no DAC) + Ipamorelin is considered the gold-standard GH protocol in the peptide community. It's favored for its physiological GH pattern, excellent tolerability, and the ability to time doses strategically (pre-sleep, pre-workout). For FDA-approved visceral fat reduction specifically, see tesamorelin.
How it works
GHRH Mimicry: Binds to GHRH receptors in the pituitary, signaling it to release stored GH. Acts like a "command" signal.
Short Half-Life Advantage: The ~30 minute half-life means each dose creates a clean GH pulse that rises and falls naturally, mimicking physiological GH patterns rather than creating a sustained bleed.
Ipamorelin Synergy: While CJC (no DAC) signals the pituitary to release GH, Ipamorelin amplifies that signal via the ghrelin receptor. Combined, GH output is substantially higher than either alone.
Reported benefits
- 01Natural pulsatile GH release pattern
- 02Excellent synergy with Ipamorelin (gold-standard stack)
- 03Strategic timing possible (sleep, workout)
- 04Less water retention vs CJC with DAC
- 05Improved sleep, recovery, and body composition
- 06Lower risk of pituitary desensitization vs DAC version
Dosing protocol
| Phase | Dose | Frequency | Duration |
|---|---|---|---|
| CJC/Ipa Stack | 100mcg CJC + 100mcg Ipa | 1–3x daily | 12 weeks |
| Pre-Sleep Dose | 100mcg each | Before bed (fasted) | Ongoing |
| Cycle | 100mcg each | 2x daily | 12 weeks on, 4 off |
Always start at the lowest effective dose and titrate up gradually.
Side effects
Common
- Mild water retention (less than DAC version)
- Tingling in hands/feet
- Mild hunger increase
- Headache in first week
Rare
- ·Hypoglycemia
- ·Pituitary desensitization with very high doses
Who should not use CJC-1295 (No DAC)
What to expect
Week 1–2
Improved sleep quality is often the first sign. Mild water retention possible.
Week 3–6
Faster recovery. Better body composition. Skin quality improving.
Month 2–3
Clear anabolic and fat-loss effects when combined with training and diet.
Month 3+
Complete the cycle and take a 4 week break before repeating.
FAQ
Do I need to use CJC (no DAC) and Ipamorelin together?
You can use either alone, but the combination is significantly more effective. They work through different receptors (GHRH vs ghrelin) and the synergy produces substantially higher GH output. The stack is widely considered the minimum effective approach.
How many times per day should I dose?
1–3 times per day. Most users dose once before sleep for recovery and sleep benefits. Advanced users add a pre-workout dose. 3x per day is reserved for those with specific body composition goals. Always dose fasted — insulin blunts GH release. Source from the community-verified supplier list.
Where to get CJC-1295 (No DAC) in the Philippines
See our community-verified supplier list with COA verification and cold-chain shipping to the Philippines.
Risk · Disclosure · Editorial Status
This page is editorial information for adults researching peptide therapy. It is not medical advice, not a prescription, and not an endorsement of any specific product, supplier, or protocol. Side effects can be serious and individual response varies. Talk to a licensed physician — ideally one with peptide-specific clinical experience — before starting any compound, adjusting a dose, or discontinuing therapy.
In the Philippines, GLP-1 medications are prescription-only under FDA Philippines regulation. Research-grade peptides occupy a regulatory gray area: import for personal research use is generally tolerated, but the Bureau of Customs reserves the right to inspect and detain shipments. Do not import for resale.
Editorial Status
Independent · Non-clinical
Affiliation
Not a clinic · Not a pharmacy
Last Updated
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