Rybelsus, oral semaglutide. The same molecule as Ozempic in a once-daily tablet. It is a prescription medicine here and stock is thinner than the injectable. No Philippine retail chain publishes a current price for it that stands up to checking, so this page does not print one. What can be said is that branch quotes land in five-figure monthly territory and do not meaningfully undercut the pens. Anyone offering a dramatically cheaper Rybelsus is worth a hard question. The oral semaglutide filing covers the tablet route properly.
Orlistat. Registered and genuinely on the shelf. Xenical 120mg is ₱51.25 a capsule at Watsons, which is about ₱4,610 a month at three capsules daily with meals. Watsons Generics orlistat 120mg is ₱24.68 a capsule, roughly ₱2,220 a month, and it is the same molecule. Alli, the 60mg over-the-counter version sold in other markets, is not registered in the Philippines. Orlistat works on fat absorption rather than appetite, the effect size in trials is modest, and the gastrointestinal side effects are the main reason people stop.
Duromine, phentermine. FDA Philippines registered in 15mg and 30mg under registration DR-XY26998, and prescription only. It is a short-term appetite suppressant of an entirely different class, not a GLP-1, and it is not a substitute for one. No major Philippine pharmacy chain publishes a retail price, and most of what surfaces in a search is classified listings and marketplace sellers. Those are not a channel worth using for a prescription-only stimulant. The Duromine filing goes through why.
Metformin, off-label. Registered, cheap and everywhere. RiteMed 500mg is ₱4.25 a tablet at Watsons and requires a prescription, so two tablets daily is about ₱255 a month. It is widely used off-label for weight, and it is honest to say that its weight effect is a fraction of what a GLP-1 does. It belongs on this list because it is a real registered option that a prescriber may raise, not because it replaces semaglutide.
A broader look at the oral category, including the products that do not work, sits in the diet pills filing. Contrave, which people ask about, shows no evidence of Philippine registration.