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Weight loss · Compound

5-Amino-1MQ

Small-molecule inhibitor of the enzyme NNMT, studied in preclinical metabolic research.

5-Amino-1MQ is not yet in the evidence datasets this site draws on, so this page makes no claim about what it does.

What is 5-Amino-1MQ

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of NNMT (nicotinamide N-methyltransferase), an enzyme involved in fat cell metabolism. It is not a peptide, although it is sold alongside research peptides. NNMT acts on nicotinamide, a building block of NAD+.

The research described for 5-Amino-1MQ is preclinical: mouse studies of diet-induced obesity. No human trial of 5-Amino-1MQ is described on this page, this page cites no primary source for the mouse work, and the compound is not in the evidence datasets this site draws on, so the page makes no claim about its effects in people.

GLP-1 medicines such as semaglutide and tirzepatide act on hormone receptors. 5-Amino-1MQ is an enzyme inhibitor, a different mechanism.

The supply index covers what to ask a seller, the COA guide explains how certificates of analysis are read, and the peptide legality guide covers Philippine regulation.

How it works

NNMT inhibition (proposed, from preclinical work): NNMT uses SAM (S-adenosylmethionine) as a methyl donor and produces 1-methylnicotinamide. Blocking NNMT is proposed to preserve SAM and raise NAD+ in fat tissue. This has not been shown in people.

NAD+ and sirtuins (proposed): higher NAD+ is proposed to activate sirtuins, enzymes that regulate mitochondrial activity and fat oxidation. This link is inferred from cell and animal work and has not been measured in human studies of 5-Amino-1MQ.

Benefits studied

5-Amino-1MQ is not yet in the evidence datasets this site draws on, so this page makes no claim about what it does. Anything published about it elsewhere should be read with its evidence level in mind: most peptides in this category have animal or cell data only.

Side effects reported

No controlled human data on adverse events for 5-Amino-1MQ is in the datasets this site draws on, so its safety in people is unknown rather than established. Effects commonly described for it are listed below; how often they occur has not been measured in a controlled trial.

  • Fatigue
  • Increased thirst
  • Appetite changes
  • Injection site reactions (injectable form)
  • Interactions with methylation pathways (theoretical)
  • Long-term effects in humans unknown

Regulatory status

The regulatory dataset this site draws on has no row for 5-Amino-1MQ.

Who should not use 5-Amino-1MQ

Everything above is research framing. If you have got as far as wanting a vial, the catalogue at Primara Labs, our partner and supplier, is the shortest way to see what is held inside the Philippines and at what price. View the Primara Labs catalogue

FAQ

What is 5-Amino-1MQ?

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of the enzyme NNMT (nicotinamide N-methyltransferase). It is not a peptide, although it is sold alongside research peptides.

What evidence exists for 5-Amino-1MQ?

The research described for 5-Amino-1MQ is preclinical: mouse studies of diet-induced obesity. No human trial is described on this page, the page cites no primary source, and the compound is not in the evidence datasets this site draws on, so no benefit or trial figure is shown.

Is 5-Amino-1MQ registered in the Philippines?

The regulatory dataset this site draws on has no row for 5-Amino-1MQ, so this page makes no claim about its registration status. The regulatory status page lists the compounds that dataset covers.

Where to get 5-Amino-1MQ in the Philippines

Primara Labs, our partner and supplier, lists their current vials on the catalogue. Prices and stock change, so check there for what is available now. View the Primara Labs catalogue

The supply index covers what to ask a seller before paying, and why quoted prices vary so widely.

Risk · Disclosure · Editorial Status

This page is editorial information for adults researching peptide therapy. It is not medical advice, not a prescription, and not an endorsement of any specific product, supplier, or protocol. Side effects can be serious and individual response varies. Talk to a licensed physician (ideally one with peptide-specific clinical experience) before starting any compound, adjusting a dose, or discontinuing therapy.

In the Philippines, GLP-1 medications are prescription-only under FDA Philippines regulation. Research-grade peptides occupy a regulatory gray area: import for personal research use is generally tolerated, but the Bureau of Customs reserves the right to inspect and detain shipments. Do not import for resale.

Editorial Status
Non-clinical
Affiliation
Not a clinic · Not a pharmacy
Last Updated
September 24, 2026

Updated